OHSU Infertility Program - IVF Results - Assisted Reproductive Results, Extended Embryo Culture Results

Assisted Reproduction (IVF) Results

From 1/1/2006 to 1/1/2007

Currently, the In Vitro Fertilization (IVF) Program at Oregon Health & Science University uses day 3 transfers as a means to optimized IVF success rates. The day of transfer is dependent upon several variables, such as the number of embryos available for transfer, age of patient, treatment category, previous patient history, etc. The decision on how many embryos to transfer is made following consultations between the patient, physician, and the embryology lab.

We are distinguished from other fertility clinics by our ability to maintain ART success rates in the country’s top 10 % while transferring an average of only 2 embryos per cycle. This greatly diminishes the serious health consequences of becoming pregnant with 3 or more babies without sacrificing your chances of becoming pregnant.

go to our study on the relationship of FSH levels as they relate to Pregnancy of women over 35

go to Preimplantation Diagnosis (PGD) results

	Own Eggs Age < 40	Own Eggs Age > 40	Donor Eggs
Number of Retrievals	198	38	29
Number of Transfers	186	36	28
Clinical Pregnancy Rate per Embryo Transfer	54 %	19 %	75 %
Clinical Pregnancy Rate per Retrieval	51 %	18 %	72 %
Mean Number Embryos Transferred	2.2	3.0	2.0
Distribution of Pregnancies
Singletons:	55	5	9
Twins:	36	2	12
Triplets:	4	0	0
>Triplets:	0	0	0

* We have experienced higher fertilization rates in the above cases in which we used Intracytoplasmic Sperm Injection (ICSI) to assure fertilization. However, in terms of pregnancy, we see no significant statistical difference comparing conventional IVF to ICSI with IVF.

How many Embryos to Transfer

Repro Endocrinologists generally transfer more than 1 embryo to increase the chances of pregnancy. However, in most cases maximum pregnancy rates are achieved with the transfer of only 2 or 3 embryos.

However, the more embryos that are transferred, the more likely the couple may experience a multiple pregnancy. Together the physician and couple carefully weigh influencing factors (age, health, embryo quality, donor eggs) to predetermine a reasonable number of embryos for transfer.

For more information on why it is important to better manage multiple gestation in assisted reproduction please read the opinion Guidelines on Number of Embryos Transferred presented by the American Society for Reproductive Medicine.